Annual Report 2023

Annual Report 2023

Non-Executive Directors

Our Board of Directors as at December 31, 2023 comprised the following eight non-executive directors:


Peter K. M. Verhaeghe

Peter K. M. Verhaeghe (photo)

Peter Verhaeghe has served as a member and chairperson of the board of arGEN-X B.V. since October 2008 and as non-executive director on our Board of Directors since July 2014.

Mr. Verhaeghe is the managing partner of VVGB Advocaten-Avocats, a corporate finance law and tax law firm, a position he has held since July 1999. He is currently lead counsel to a number of Belgian, Dutch, French, U.S. and Swiss life sciences companies. Mr. Verhaeghe has served on the boards of directors of Participatiemaatschappij Vlaanderen NV since May 2018 and miDiagnostics NV since April 2020. He has also served as chairman of the board of Haretis SA (Luxembourg) since March 2011 and as chairman of the LP & advisory committee of Bioqube Factory Fund I NV since September 2020. Mr. Verhaeghe previously served as a member of the board of directors of CzechPak Manufacturing s.r.o., Innogenetics NV (now Fujirebio Europe N.V.), Tibotec-Virco NV, and Biocartis SA. He was also the president of the board of directors of Merisant France SAS, a member of the management board of Merisant Company 2 sàrl., and chairman of the board of directors of PharmaNeuroBoost NV.

Mr. Verhaeghe holds a degree in law from the University of Leuven and an LL.M. degree from Harvard Law School.

Dr. Werner Lanthaler (until February 27, 2023)

Dr. Werner Lanthaler (photo)

Dr. Werner Lanthaler served as a member of our Board of Directors from July 2014 until February 27, 2023.

Dr. Lanthaler served as the CEO of Evotec SE until January 2024, a global drug discovery and development organization, a position he held since March 2009. He also serves on the supervisory board of AC Immune SA (Switzerland).

Dr. Lanthaler holds a degree in psychology, a Ph.D. in business administration from Vienna University of Economics and Business, and a Master’s degree in public administration from Harvard University.

 


Mr. Steve Krognes (effective February 27, 2023)

Mr. Steven Krognes (photo)

Mr. Krognes has served as a member of our Board of Directors and as a chairperson of our audit and compliance committee since February 27, 2023.

Mr. Krognes also serves on the boards of directors of Guardant Health, Inc., Denali Therapeutics, Inc., and Gritstone bio, Inc. In September 2023, he also was appointed to the board of directors of ClayvstBio. He previously served on the boards of directors of RLS Global AB and Corvus Pharmaceuticals, Inc. Mr. Krognes was the founding chief financial officer of Denali Therapeutics, Inc. (Denali Therapeutics), from 2015 until retiring from that position in April 2022. In that role, he built and led the finance team as well as supervising the IT and facilities functions. He then joined the board of directors of Denali Therapeutics. Mr. Krognes led successful financings for Denali Therapeutics, including its initial public offering in 2017, and contributed significantly to the company’s strategy, growth and strong financial position. His extensive leadership experience in the biotech and pharmaceutical industries includes 12 years in total at Roche and Genentech, Inc., during which Mr. Krognes served as chief financial officer of Genentech, Inc. for six years and global head of Roche’s mergers & acquisition team for six years. He also chaired the Genentech Access to Care Foundation and represented Genentech on the board and executive committee of the California Life Science Association. Before that, Mr. Krognes worked as an investment banker at Goldman Sachs, as a management consultant at McKinsey & Company, and as a venture capitalist in Scandinavia.

Mr. Krognes holds a Master’s of Business Administration (MBA) from Harvard Business School and a Bachelor’s of Science in economics from the Wharton School of the University of Pennsylvania.

Dr. J. Donald deBethizy

Dr. J. Donald deBethizy (photo)

Dr. deBethizy has 30 years of experience in research and development, as well as financial, business and operating management, and board work in the biotechnology and consumer products industries.

He is the president of White City Consulting ApS, a consulting company that specializes in advising technology-focused companies. Dr. deBethizy currently serves on the boards of directors of Lophora ApS and Proterris, Inc. and as a board advisor for Cereno Scientific AB.

Previously, Dr. deBethizy served as president and CEO of Santaris Pharma A/S until October 2014, when the company was sold to Roche. From March 1997 to June 2012, Dr. deBethizy was co-founder and CEO of Targacept Inc. (Targacept), a U.S. biotechnology company listed on Nasdaq. From June 2012 to May 2013, he was special advisor to the chairman of Targacept’s board of directors. From May 2013 to November 2014, Dr. deBethizy served as executive chairman of Contera Pharma ApS until it was sold to Bukwang Pharma, and from July 2015 to November 2017, he served as chairman of Rigontec GmbH until it was sold to Merck Inc. He previously served as chairman of the boards of directors of Albumedix Ltd (sold to Sartorius AG in September 2022), Saniona AB, and TME Pharma NV and AG. Dr. deBethizy was also a member of the boards of directors of Asceneuron SA, Serendex Pharmaceuticals A/S, Enbiotix Inc., Ligocyte Pharmaceuticals until it was sold to Takeda Pharmaceutical Co Ltd, Biosource Inc., and NOXXON Pharma N.V. Dr. deBethizy has held adjunct appointments at Wake Forest University Babcock School of Management, Wake Forest University School of Medicine, and Duke University.

Dr. deBethizy holds a Bachelor’s of Science in biology from the University of Maryland, College Park and a Master’s of Science and a Ph.D. in toxicology from Utah State University.

Dr. Pamela Klein

Dr. Pamela Klein (photo)

Dr. Pamela Klein has served as a member of our Board of Directors since April 2016.

Since 2008, Dr. Klein has been a principal and founder of PMK BioResearch, a company offering strategic consulting in oncology drug development to corporate boards, management teams and the investment community. She has also been a venture partner in Ysios Capital Partners, SGIEC, S.A.U. since 2023. She currently serves as a member of the board of directors of several companies including I-Mab and Patrys Ltd; as well as various scientific advisor boards. In 2023, Dr. Klein also joined the boards of directors of Frontier Medicines Corp, Ona Therapeutics SL, and Sardona Therapeutics, Inc. Previously, Dr. Klein served on the board of directors of FStar Therapeutics, Inc. until March 2023, Jiya Acquisition Corp, and Spring Bank Pharmaceuticals, Inc. until its merger with F-Star Therapeutics in July 2020. Dr. Klein previously spent seven years at the National Cancer Institute as research director of the NCI-Navy Breast Center, after which she joined Genentech as vice president of development until 2001. She also served as chief medical officer for Intellikine, Inc., which was acquired by Takeda American Holdings.

Dr. Klein holds a Bachelor’s degree in biology from California State University and an M.D. from Stritch School of Medicine, Loyola University Chicago and is trained in internal medicine and medical oncology.


Anthony A. Rosenberg

Msc. Anthony A. Rosenberg (photo)

Anthony A. Rosenberg has served as a member of our Board of Directors since April 2017.

He currently serves as CEO of TR Advisory Services GmbH, his own consultancy firm advising on business development, licensing, and mergers and acquisitions. Mr. Rosenberg also currently serves as chairman of the boards of directors of Oculis SA and Cullinan Oncology. Previously Mr. Rosenberg held the positions of Managing Director at MPM Capital, a venture capital firm (2015 until 2020); head of M&A and Licensing of Novartis International (2013 to 2015); and head of business development and licensing at Novartis Pharma (2005 to 2012). Mr. Rosenberg also previously served on the boards of directors of SiO2 Material Science (until March 2023), Radius Health Inc., TriNetX, Inc., iOmx Therapeutics AG, and Clinical Ink, Msc.

Mr. Rosenberg has a Bachelor of Science with honors from the University of Leicester and a Master’s of Science in physiology from the University of London.

James M. Daly

James M. Daly (photo)

James M. Daly has served as a member of our Board of Directors since May 2018. Mr. Daly currently also serves as a director of Acadia Pharmaceuticals, Inc., Bellicum Pharmaceuticals, Inc., and Madrigal Pharmaceuticals, Inc. He was formerly a member of the board of Chimerix, Inc. and Halozyme.

In 1985, he joined GlaxoSmithKline where he held various positions, including senior vice president of the respiratory division with full responsibility for sales, marketing and medical affairs. Mr. Daly moved to Amgen in 2002 where he was senior vice president for the North America commercial operations until 2011. In 2012, he joined Incyte Corp, a publicly-traded company focused on oncology and inflammation, where he was chief commercial officer until June 2015.

Mr. Daly holds a Bachelor’s of Science and an MBA from the University at Buffalo, State University of New York.


Camilla Sylvest

Camilla Sylvest (photo)

Camilla Sylvest has served as a member of our Board of Directors since September 2022. Ms. Sylvest currently serves as the executive vice president of commercial strategy and corporate affairs of Novo Nordisk A/S.

Ms. Sylvest has more than 27 years of working experience within Novo Nordisk A/S and was based in Switzerland, Denmark, Germany, Malaysia, and Mainland China. Over the years, Ms. Sylvest has headed up Novo Nordisk A/S affiliates of growing size and complexity in Europe. She was also corporate vice president of the business area Oceania and Southeast Asia and senior vice president and general manager of the Novo Nordisk A/S region of Mainland China. Ms. Sylvest also serves as the vice chair of Danish Crown A/S.

Ms. Sylvest holds a Master’s of Science in economics from the University of Southern Denmark and an executive MBA from the Scandinavian Management Institute.

Ana Cespedes

Ana Cespedes (photo)

Ana Cespedes has served as a member of our Board of Directors since December 2022. Ms. Cespedes is the chief operating officer of the International AIDS Vaccine Initiative (IAVI), a global organization dedicated to developing accessible vaccines and antibodies for infectious diseases.

Prior to joining IAVI, Ms. Cespedes held several roles at Merck KGaA, most recently serving as global head of strategy and engagement, government, and public affairs. She founded and led the global market access and pricing function for the company and worked with stakeholders to communicate the clinical, economic, and societal value of innovative medicines. Prior to that, Ms. Cespedes led the first integrated corporate affairs group at Serono Iberia and Merck Spain, was managing director of the Spanish branch of the company’s nonprofit organization, and worked as a senior consultant at Arthur Andersen. Ms. Cespedes is a founding member of the National Congress of Corporate Affairs in Spain, the London School of Economics Market Access Academy, and the Cooperation for Oncology Data. She is also the founder of Living Mindfulness S.L. Ms. Cespedes is also a member of the steering committee of ProPatiens Institute.

Ms. Cespedes holds a Bachelor’s of Pharmacy and a PhD from the Complutense University of Madrid, a Master in General Management (PDG) from IESE Business School and an Executive Certificate on Strategy and Innovation from the Massachusetts Institute of Technology.

The following table sets forth certain information with respect to the current non-executive members of our Board of Directors, including their ages, as at December 31, 2023:

Name

 

Age

 

Gender

 

Position

 

Nationality

 

Date of Initial Appointment

 

Date of last (re-) Appointment

 

Term Expiration

Peter K. M. Verhaeghe

 

65

 

M

 

Non-Executive Director (chairperson)

 

Belgium

 

October 15, 2008

 

May 10, 2022

 

2026

Werner Lanthaler1)

 

55

 

M

 

Non-Executive Director (vice-chairperson)

 

Austria

 

July 9, 2014

 

May 10, 2022

 

2024

Steve Krognes1)

 

55

 

M

 

Non-Executive Director

 

U.S. and Norway

 

February 27, 2023

 

February 27, 2023

 

2027

J. Donald deBethizy

 

73

 

M

 

Non-Executive Director

 

U.S.

 

May 13, 2015

 

May 2, 2023

 

2025

Pamela Klein

 

62

 

F

 

Non-Executive Director

 

U.S.

 

April 28, 2016

 

May 12, 2020

 

2024

Anthony A. Rosenberg

 

70

 

M

 

Non-Executive Director

 

UK

 

April 26, 2017

 

May 11, 2021

 

2025

James M. Daly

 

62

 

M

 

Non-Executive Director

 

U.S.

 

May 8, 2018

 

May 10, 2022

 

2026

Camilla Sylvest

 

51

 

F

 

Non-Executive Director

 

Denmark

 

September 8, 2022

 

September 8, 2022

 

2026

Ana Cespedes

 

50

 

F

 

Non-Executive Director

 

Spain

 

December 12, 2022

 

December 12, 2022

 

2026

1)

Werner Lanthaler resigned effective February 27, 2023 and was succeeded by Steve Krognes effective February 27, 2023.

The address for our non-executive directors is our registered office, Laarderhoogtweg 25, 1101 EB Amsterdam, the Netherlands.

The following table sets forth the companies and partnerships of which the current non-executive members of our Board of Directors have been a member of the administrative, management or supervisory bodies or partner at any time in the previous five years, indicating whether or not the individual is still a member of the administrative, management or supervisory bodies or partner, as of the date of this Annual Report, other than argenx or our subsidiaries:

Name

 

Current

 

Past

Peter K. M. Verhaeghe

 

VVGB Advocaten – Avocats

 

PharmaNeuroBoost NV

 

 

 

 

Biocartis SA

 

 

Participatiemaatschappij Vlaanderen NV

 

Fujirebio Europe NV (formerly Innogenetics NV)

 

 

miDiagnostics NV

 

Tibotec-Virco NV

 

 

 

 

Merisant France SAS

 

 

 

 

Merisant Company 2 sàrl

 

 

 

 

CzechPak Manufacturing s. r. o.

 

 

 

 

Bever Zwerfsport BV

 

 

 

 

Bioqube Factory Fund I NV

 

 

 

 

Haretis SA

 

 

 

 

 

Werner Lanthaler1)

 

 

 

Bioxell SpA

 

 

 

 

Pantec Biosolutions AG

 

 

 

 

AC Immune SA

 

 

 

 

Evotec SE

 

 

 

 

 

J. Donald deBethizy

 

White City Consulting ApS

 

Rigotec GmbH

 

 

Newron Pharmaceuticals SpA

 

TME Pharma NV and AG

 

 

Protteris, Inc.

 

Saniona AB

 

 

Lophora ApS

 

Albumedix A/S

 

 

 

 

Asceneuron SA

 

 

 

 

Albumin Holdings ApS

 

 

 

 

Innovent LLC

 

 

 

 

 

Pamela Klein

 

 

 

Olema Oncology

 

 

 

 

Jiya Acquisition Corp.

 

 

 

 

PMK BioResearch

 

 

 

 

Patrys Limited

 

 

 

 

I-Mab

 

 

 

 

F-Star Therapeutics, Inc.

 

 

 

 

 

Anthony A. Rosenberg

 

Cullinan Oncology Inc.

 

Radius Health, Inc.

 

 

Oculis SA

 

TriNetX, Inc.

 

 

 

 

Clinical Ink, Inc.

 

 

 

 

iOmx Therapeutics AG

 

 

 

 

MPM Capital

 

 

 

 

SiO2 Material Science

 

 

 

 

TR Advisory Services GmbH

 

 

 

 

 

James M. Daly

 

Acadia Pharmaceuticals Inc.

 

Chimerix, Inc.

 

 

Halozyme Therapeutics, Inc.

 

Coherus Biosciences

 

 

Bellicum Pharmaceuticals, Inc.

 

 

 

 

Madrigal Pharmaceuticals

 

 

 

 

 

 

 

Camilla Sylvest

 

Novo Nordisk

 

World Diabetes Foundation

 

 

Crown A/S

 

 

 

 

 

 

 

Ana Cespedes

 

International AIDS Vaccine Initiative (IAVI)

 

Instituto ProPatients

 

 

 

 

Merck KGaA

 

 

 

 

Merck Spain

 

 

 

 

Serono Iberia

 

 

 

 

Arthur Andersen

 

 

 

 

 

Steve Krognes

 

Denali Therapeutics Inc.

 

R/S Global

 

 

Guardant Health, Inc.

 

Corvus Pharmaceuticals Inc.

 

 

Gritstone bio Inc.

 

 

 

 

ClavystBio

 

 

1)

Werner Lanthaler resigned effective February 27, 2023 and was succeeded by Steve Krognes effective February 27, 2023.