Management Confirmations

With due regard to best practice principle 1.4.3 of the DCGC, we confirm that:

1. This Annual Report provides sufficient insights into any failings in the effectiveness of the internal risk management and control systems, as is further substantiated in section “Risk Factors”, and section “Risk Appetite & Control”;
2. The risk- and control systems described herein, particularly in paragraph “Financial Risks and Controls” provide reasonable assurance that the financial reporting does not contain any material inaccuracies;
3. We confirm that we expect that our existing cash and cash equivalents and current financial assets will enable us to fund our operating expenses and capital expenditure requirements through at least the next twelve months. On the basis of the current state of affairs, it is justified that the financial reporting is prepared on a going concern basis; and
4. This Annual Report, particularly section “Risk” states those material risks and uncertainties that are relevant to the expectation of our continuity for the period of twelve months after the preparation of this Annual Report. The aforementioned statement does not in any way limit the relevance or applicability of the Risk Factors set out in this Annual Report to the aforementioned period of twelve months.

Signed on behalf of argenx SE